Autoimmunedisease相关论文
生物钟的形成与一系列生物钟基因及其调控基因构成的分子环路有关,其编码的蛋白可影响炎症细胞因子和趋化因子的表达,调控免疫细胞的......
A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthriti
OBJECTIVE;The interleukin (IL)-12 cytokine family is closely related to the development of T helper cells,which are resp......
As a cellular bulk degradation and survival mechanism,autophagy is implicated in diverse biological processes.Genome-wid......
近年来,越来越多研究证据表明免疫球蛋白E(immunoglobulin E,IgE)在自身免疫和炎症反应中起重要作用,其中最受关注的是IgE在系统性红......
Purpose: This study aims to investigate the roles of PDCD5 in autoimmune disease and to probe into its molecular mechani......
Bamboo node:an unusual cause of dysphonia in a Filipino patient with mixed connective tissue disease
Background: Bamboo node is a rare vocal cord pathology causing dysphonia among patients with autoimmune disorders.These ......
Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammat
Iron deposition is frequently observed in human autoinflammatory diseases,but its functional significance is largely unk......
Poor blood and stem/progenitor cell supplies underlie wound healing impairment in diabetic patients.Induced pluripotent ......
Background and Aims.Currently published data regarding the relationship between plasma/serum leptin levels and systemic ......
An innovative vaccine composed of the BAFF protein containing a unnatural amino acid triggers the pr
B cell-activating factor(BAFF)plays a fundamental role in B lymphocyte survival and homeostasis,and aberrant BAFF signal......
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CircRNAs produced from back-splicing of exons of pre-mRNAs are widely expressed,but current understanding of their f......
Long noncoding RNA(lncRNA),with size larger than 200 nucleotides,is a new class of noncoding RNA.Emerging evidence h......
目的探讨抗谷氨酸脱羧酶-65(GAD65)抗体相关神经免疫病的临床特点、辅助检查结果、治疗及临床预后的情况。方法收集2018年10月至2020......
LIGHT/TNFSF14是近年来发现的肿瘤坏死因子超家族成员,具有共刺激T淋巴细胞、诱导iDC成熟、促进肿瘤细胞凋亡的生物学功能,在自身免疫......
Clinical manifestation and humoral immuno-function of myasthenia gravis patients with abnormal and n
BACKGROUND: Myasthenia gravis (MG) is an autoimmune disease which mainly affects neuromuscular junctions. The ages, modi......
Current Understanding on the Immunological Functions of Tumor Necrosis Factor-Related Apoptosis-Indu
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in various tumor cel......
Inbred strains of mice and rats are widely used in preclinical investigations evaluating the effectiveness of glycan-bas......
钟样受体4(TLR4)是钟样受体家族的成员之一,能识别宿主源性激动剂,在固有免疫和后天免疫中发挥重要作用.近来有研究发现损伤组织释......
B细胞的主要功能是分泌抗体和呈递抗原,并以此起始和活化免疫系统发挥正性调节作用。新近研究表明,一类具有负性免疫调节功能的 B 细......
自身免疫性疾病是由机体免疫效应细胞或免疫效应分子针对自身组织或细胞产生免疫应答,最终导致组织损伤或器官功能障碍的炎症性疾......
白细胞介素21(IL-21)是IL-2家族中的新成员,主要由活化的CD41细胞和自然杀伤(NKT)细胞合成和分泌.白细胞介素21受体(IL-21R)主要表......
干燥综合征是一种以侵犯泪腺、唾液腺等外分泌腺体为主的慢性自身免疫性疾病,其心血管并发症比较少见,主要为心包炎、左室舒张功能......
可溶性CD163是由单核细胞/巨噬细胞分泌的血清可溶性CD163(sCD163),存在于血清及其他组织液中,与炎性反应的发生相关,被认为是单核......
1 Clinical data rnNeuromyotonia is an uncommon syndrome of spontaneous and continuous muscle fiber activity,of which,the......
1 概念与名称自身免疫性疾病 (autoimmunedisease ,AD)泛指机体免疫效应细胞如细胞毒性T淋巴细胞 (CTL)、自然杀伤细胞(NK)、巨噬细胞等 ,或免疫效应分子 (......
烟雾病是一种罕见的颅内血管病变,通过对干燥综合征所致成人烟雾病单发病例资料及临床特征分析发现,烟雾病在儿童多为先天性血管发育......
Current Understanding on the Immunological Functions of Tumor Necrosis Factor-Related Apoptosis-Indu
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in various tumor cel......